Detail
| LncRNA Name | TUG1 |
| Synonyms | TUG1, LINC00080, NCRNA00080, TI-227H, FLJ20618 |
| Region | GRCh38_22:30969245-30979395 Sequence |
| Ensembl | ENSG00000253352 |
| RefSeq | NR_002323 |
| Circulating | ✔ |
| Drug-resisitant | ✘ |
| Prognostic | ✔ |
| MiRNA | ✘ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✘ |
| Cancer Name | osteosarcoma |
| ICD-0-3 | M9180/3 |
| Methods | qPCR etc. |
| Sample | blood, osteosarcoma tissues |
| Expression Pattern | up-regulated |
| Function Description | TUG1 was significantly overexpressed in the osteosarcoma tissues compared with matched adjacent normal tissues and was closely correlated with tumor size, post-operative chemotherapy, and Enneking surgical stage. Upregulation of TUG1 strongly correlated with poor prognosis and was an independent prognostic indicator for overall survival and progression-free survival. |
| Pubmed ID | 26499949 |
| Year | 2016 |
| Title | Upregulation of long non-coding RNA TUG1 correlates with poor prognosis and disease status in osteosarcoma. |
| External Links |
| Links for TUG1 | GenBank HGNC lncrnadb Noncode |
| Links for osteosarcoma | Omim Cosmic |
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