Detail
LncRNA Name | TUG1 |
Synonyms | TUG1, LINC00080, NCRNA00080, TI-227H, FLJ20618 |
Region | GRCh38_22:30969245-30979395 Sequence |
Ensembl | ENSG00000253352 |
RefSeq | NR_002323 |
Circulating | ✘ |
Drug-resisitant | ✘ |
Prognostic | ✘ |
MiRNA | ✘ |
Variant | ✘ |
TF | ✘ |
Methylation | ✘ |
Cancer Name | colorectal cancer |
ICD-0-3 | C19.9 |
Methods | qPCR, RNAi, Western blot, Flow cytometry assay, Cell proliferation assay etc. |
Sample | CRC tissues, cell lines (HCT116, LoVo, RKO, SW620, and SW480) |
Expression Pattern | up-regulated |
Function Description | Here, we reported that TUG1 was upregulated in CRC. Further experiments revealed that TUG1 knockdown significantly inhibited cell proliferation, migration and invasion of CRC in vitro. |
Pubmed ID | 27421138 |
Year | 2016 |
Title | Long non-coding RNA TUG1 promotes colorectal cancer metastasis via EMT pathway. |
External Links |
Links for TUG1 | GenBank HGNC lncrnadb Noncode |
Links for colorectal cancer | Omim Cosmic |
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