Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name TUG1
   Synonyms TUG1, LINC00080, NCRNA00080, TI-227H, FLJ20618
   Region GRCh38_22:30969245-30979395    Sequence
   Ensembl ENSG00000253352
   RefSeq NR_002323
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name gastric cancer
   ICD-0-3 C16  
   Methods qPCR, Western blot, Luciferase reporter assay etc.
   Sample Gastric carcinoma tissues, cell lines (GES-1, Bgastric cancer-823, Mgastric cancer-803, Sgastric cancer-7901, MKN28)
   Expression Pattern up-regulated
   Function Description

downregulation of miR-381 by lncRNA-TUG1 promoted the metastasis of GC cells by inhibiting SOX4.

   Pubmed ID 28927144
   Year 2017
   Title MiR-381 inhibits migration and invasion in human gastric carcinoma through downregulatedting SOX4
   External Links
   Links for  TUG1 GenBank       HGNC       lncrnadb       Noncode
   Links for  gastric cancer Omim       Cosmic

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