Detail
LncRNA Name | TUSC7 |
Synonyms | TUSC7, LINC00902, LSAMP-AS1, LSAMP-AS3, LSAMPAS3, NCRNA00295, LOC285194 |
Region | GRCh38_3:116709235-116723581 Sequence |
Ensembl | ENSG00000243197 |
RefSeq | NR_015391 |
Circulating | ✘ |
Drug-resisitant | ✘ |
Prognostic | ✘ |
MiRNA | ✔ |
Variant | ✘ |
TF | ✘ |
Methylation | ✘ |
Cancer Name | colon cancer |
ICD-0-3 | C18 |
Methods | qPCR, RNAi, Western blot, ChIP, Luciferase reporter assay, Cell proliferation assay, ISH etc. |
Sample | cell lines (MCF-7, HCT-8, A549, HCT-116) |
Expression Pattern | differential expression |
Function Description | To evaluate the biological consequence of p53 induction of loc285194 and the role of loc285194 in tumorigenesis, we ectopically expressed loc285194 in HCT-116 WT and MCF-7 cells for cell proliferation assays. As expected, loc285194 significantly inhibited tumor cell growth. |
Pubmed ID | 23558749 |
Year | 2013 |
Title | LncRNA loc285194 is a p53-regulated tumor suppressor. |
External Links |
Links for TUSC7 | GenBank HGNC lncrnadb Noncode |
Links for colon cancer | Omim Cosmic |
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