Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name TUSC7
   Synonyms TUSC7, LINC00902, LSAMP-AS1, LSAMP-AS3, LSAMPAS3, NCRNA00295, LOC285194
   Region GRCh38_3:116709235-116723581    Sequence
   Ensembl ENSG00000243197
   RefSeq NR_015391
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name colon cancer
   ICD-0-3 C18  
   Methods qPCR, RNAi, Western blot, ChIP, Luciferase reporter assay, Cell proliferation assay, ISH etc.
   Sample cell lines (MCF-7, HCT-8, A549, HCT-116)
   Expression Pattern differential expression
   Function Description

To evaluate the biological consequence of p53 induction of loc285194 and the role of loc285194 in tumorigenesis, we ectopically expressed loc285194 in HCT-116 WT and MCF-7 cells for cell proliferation assays. As expected, loc285194 significantly inhibited tumor cell growth.

   Pubmed ID 23558749
   Year 2013
   Title LncRNA loc285194 is a p53-regulated tumor suppressor.
   External Links
   Links for  TUSC7 GenBank       HGNC       lncrnadb       Noncode
   Links for  colon cancer Omim       Cosmic

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