Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name TUSC7
   Synonyms TUSC7, LINC00902, LSAMP-AS1, LSAMP-AS3, LSAMPAS3, NCRNA00295, LOC285194
   Region GRCh38_3:116709235-116723581    Sequence
   Ensembl ENSG00000243197
   RefSeq NR_015391
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name pancreatic ductal adenocarcinoma
   ICD-0-3 C25.3  M8500/3
   Methods qPCR etc.
   Sample PDAC tissues, cell lines (HPDE6-C7, PANC-1, BxPC-3, AsPC-1, and PL45)
   Expression Pattern down-regulated
   Function Description

Our data showed that the relative level of LOC285194 in PDAC cells was significantly lower than that in normal human pancreatic duct epithelial cell line. Also, the expression of LOC285194 in PDAC tissues was significantly lower than that in adjacent non-tumor tissues. By statistical analyses, low LOC285194 expression was observed to be closely correlated with clinical stage, lymphnode metastasis and liver metastasis.

   Pubmed ID 25550852
   Year 2014
   Title Expression of long non-coding RNA LOC285194 and its prognostic significance in human pancreatic ductal adenocarcinoma.
   External Links
   Links for  TUSC7 GenBank       HGNC       lncrnadb       Noncode
   Links for  pancreatic ductal adenocarcinoma Omim       Cosmic

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