Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name TUSC7
   Synonyms TUSC7, LINC00902, LSAMP-AS1, LSAMP-AS3, LSAMPAS3, NCRNA00295, LOC285194
   Region GRCh38_3:116709235-116723581    Sequence
   Ensembl ENSG00000243197
   RefSeq NR_015391
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name gastric cancer
   ICD-0-3 C16  
   Methods microarray, qPCR, RNAi etc.
   Sample gastric cancer tissues
   Expression Pattern down-regulated
   Function Description

The results indicated that TUSC7 was downregulated in GC samples and was an independent prognostic indicator of disease-free survival (DFS) and disease-specific survival (DSS) in GC patients.The results indicated that TUSC7 is a p53-regulated tumour suppressor that acts in part by repressing miR-23b and that TUSC7 may be a key regulatory hub in GC.

   Pubmed ID 25765901
   Year 2015
   Title Reciprocal repression between TUSC7 and miR-23b in gastric cancer.
   External Links
   Links for  TUSC7 GenBank       HGNC       lncrnadb       Noncode
   Links for  gastric cancer Omim       Cosmic

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