Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

LncRNA centric

Cancer centric

Advanced search

Drug resistant

Circulating

Prognosis

Detail


   LncRNA Name TUSC7
   Synonyms TUSC7, LINC00902, LSAMP-AS1, LSAMP-AS3, LSAMPAS3, NCRNA00295, LOC285194
   Region GRCh38_3:116709235-116723581    Sequence
   Ensembl ENSG00000243197
   RefSeq NR_015391
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name colorectal cancer
   ICD-0-3 C19.9  
   Methods qPCR etc.
   Sample CRC tissues, cell lines (CaCO-2, HCT8, LoVo, CCC-HIE-2 etc.)
   Expression Pattern down-regulated
   Function Description

The relative expression levels of LOC285194 was significantly lower in tumor tissues and colorectal cancer cell lines compared with adjacent normal tissues and normal intestinal mucous cell line. In addition, low expression of LOC285194 was correlated with larger tumor size, higher tumor stage, and more distant metastasis. Our data indicate that LOC285194 might be a novel prognostic indicator in colorectal cancer and may be a potential target for diagnosis and gene therapy.

   Pubmed ID 23680400
   Year 2013
   Title Low expression of LOC285194 is associated with poor prognosis in colorectal cancer.
   External Links
   Links for  TUSC7 GenBank       HGNC       lncrnadb       Noncode
   Links for  colorectal cancer Omim       Cosmic

CopyRight © College of Bioinformatics Science and Technology, Harbin Medical University, China.