Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name uc.8+
   Synonyms FAM138F, F379
   Region GRCh38_19:76163-77686    Sequence
   Ensembl ENSG00000282591
   RefSeq NR_026820
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name bladder cancer
   ICD-0-3 C67  
   Methods microarray, qPCR, RNAi, Cell proliferation assay etc.
   Sample bladder cancer tissues, cell lines (J82 and RT112)
   Expression Pattern up-regulated
   Function Description

The results showed an increase of 6.5 fold for uc.8+, an increase of 2.45 fold for uc.339+, a decrease of 0.105 fold for uc.195+, and a decrease of 0.25 fold for uc.217+A in BlCa tissues compared with NBE. These results are consistent with the trend shown by microarray analysis results and indicate the primary role that uc.8+ may have in BlCa onset and progression.

   Pubmed ID 26943042
   Year 2016
   Title Long non-coding RNA containing ultraconserved genomic region 8 promotes bladder cancer tumorigenesis
   External Links
   Links for  uc.8+ GenBank       HGNC       lncrnadb       Noncode
   Links for  bladder cancer Omim       Cosmic

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