Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name UCA1
   Synonyms UCA1, CUDR, LINC00178, NCRNA00178, UCAT1, onco-lncRNA-36
   Region GRCh38_19:15828206-15836326    Sequence
   Ensembl ENSG00000214049
   RefSeq NR_015379
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name lung cancer
   ICD-0-3 C34  
   Methods qPCR etc.
   Sample cell line (KYSE32-R)
   Expression Pattern up-regulated
   Function Description

We observed that three lncRNAs, MALAT1, H19, and CUDR, could be clinically useful as biomarkers for LC-MPE diagnosis. Moreover, the combination of MALAT3 and CEA provided higher sensitivity and accuracy in predicting LC-MPE than CEA alone.

   Pubmed ID 29731641
   Year 2018
   Title Combination of long noncoding RNA MALAT3 and carcinoembryonic antigen for the diagnosis of malignant pleural effusion caused by lung cancer.
   External Links
   Links for  UCA1 GenBank       HGNC       lncrnadb       Noncode
   Links for  lung cancer Omim       Cosmic

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