Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name UCA1
   Synonyms UCA1, CUDR, LINC00178, NCRNA00178, UCAT1, onco-lncRNA-36
   Region GRCh38_19:15828206-15836326    Sequence
   Ensembl ENSG00000214049
   RefSeq NR_015379
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name colon cancer
   ICD-0-3 C18  
   Methods qPCR etc.
   Sample colon cancer tissues
   Expression Pattern up-regulated
   Function Description

Compared with adjacent normal tissues, UCA1 was significantly upregulated in colon cancer tissues, especially in cases with LNM and advanced TNM stages. High UCA1 expression was associated with LMN, higher pT category, and advanced TNM stages. Patients with high UCA1 expression had worse survival time than those with low UCA1 expression. Furthermore, plasma levels of UCA1 in colon cancer patients were significantly higher than those of controls.

   Pubmed ID 26885155
   Year 2015
   Title Clinical significance of urothelial carcinoma associated 1 in colon cancer.
   External Links
   Links for  UCA1 GenBank       HGNC       lncrnadb       Noncode
   Links for  colon cancer Omim       Cosmic

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