Detail
| LncRNA Name | BLACAT1 |
| Synonyms | BLACAT1, LINC00912, UBC1, onco-lncRNA-30, linc-UBC1, onco-lncRNA-30 |
| Region | GRCh38_1:205434886-205437879 Sequence |
| Ensembl | ENSG00000281406 |
| RefSeq | NR_103783 |
| Circulating | ✘ |
| Drug-resisitant | ✘ |
| Prognostic | ✔ |
| MiRNA | ✘ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✘ |
| Cancer Name | gastric cancer |
| ICD-0-3 | C16 |
| Methods | qPCR, RNAi etc. |
| Sample | gastric cancer tissues, cell lines (BGC-823, SGC-7901, AGS, MKN-45, HGC-27 etc.) |
| Expression Pattern | up-regulated |
| Function Description | We found that linc-UBC1 was significantly upregulated in gastric cancer tissues compared to adjacent normal tissues. Furthermore, high linc-UBC1 expression was associated with lymph-node metastasis, tumor size, TNM stage and poorer prognosis. Inhibition of linc-UBC1 suppressed the proliferation, motility and invasion of gastric cancer cells.Inhibition of linc-UBC1 suppressed the proliferation, motility and invasion of gastric cancer cells. |
| Pubmed ID | 25755750 |
| Year | 2015 |
| Title | Long noncoding RNA linc-UBC1 is negative prognostic factor and exhibits tumor pro-oncogenic activity in gastric cancer. |
| External Links |
| Links for BLACAT1 | GenBank HGNC lncrnadb Noncode |
| Links for gastric cancer | Omim Cosmic |
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