Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name UCA1
   Synonyms UCA1, CUDR, LINC00178, NCRNA00178, UCAT1, onco-lncRNA-36
   Region GRCh38_19:15828206-15836326    Sequence
   Ensembl ENSG00000214049
   RefSeq NR_015379
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name hepatocellular carcinoma
   ICD-0-3 C22.0  M8170/3
   Methods qPCR
   Sample hepatocellular carcinoma tissues
   Expression Pattern up-regulated
   Function Description

High expression of serum UCA1 was significantly associated with a high tumor grade, large tumor size,positive vascular invasion, and advanced TNM stage.a high serum UCA1 level was an independent unfavorable prognostic factor for HCC. High levels of UCA1 in HCC tumor tissues are closely related to large tumor size, vascular invasion,advanced TNM stage, and poor postoperative survival.

   Pubmed ID 28856933
   Year 2017
   Title Serum long noncoding RNA urothelial carcinoma-associated 1: A novel biomarker for diagnosis and prognosis of hepatocellular carcinoma.
   External Links
   Links for  UCA1 GenBank       HGNC       lncrnadb       Noncode
   Links for  hepatocellular carcinoma Omim       Cosmic

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