Detail
| LncRNA Name | BOKAS |
| Synonyms | BOK-AS1, BOK-AS, BOKAS, NAToB, NCRNA00151 |
| Region | NA Sequence |
| Ensembl | NA |
| RefSeq | NA |
| Circulating | ✘ |
| Drug-resisitant | ✘ |
| Prognostic | ✔ |
| MiRNA | ✘ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✘ |
| Cancer Name | testicular cancer |
| ICD-0-3 | C62 |
| Methods | qPCR etc. |
| Sample | cell line (Hela) |
| Expression Pattern | up-regulated |
| Function Description | The mRNA expression of BOKAS was only detected in testis and certain cancer tissues but not in other normal adult tissues examined. Overexpression of BOKAS alone exhibited no significant anti- or pro-apoptotic activity but it was able to inhibit Bok-induced apoptosis in HeLa cells. Our results suggest that BOKAS may function specifically in the human testis, where it serves as an antisense molecule to regulate Bok-induced apoptosis. |
| Pubmed ID | 19287972 |
| Year | 2009 |
| Title | A natural antisense transcript, BOKAS, regulates the pro-apoptotic activity of human Bok. |
| External Links |
| Links for BOKAS | GenBank HGNC lncrnadb Noncode |
| Links for testicular cancer | Omim Cosmic |
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