Detail
| LncRNA Name | UCA1 |
| Synonyms | UCA1, CUDR, LINC00178, NCRNA00178, UCAT1, onco-lncRNA-36 |
| Region | GRCh38_19:15828206-15836326 Sequence |
| Ensembl | ENSG00000214049 |
| RefSeq | NR_015379 |
| Circulating | ✘ |
| Drug-resisitant | ✘ |
| Prognostic | ✘ |
| MiRNA | ✘ |
| Variant | ✘ |
| TF | ✔ |
| Methylation | ✘ |
| Cancer Name | bladder cancer |
| ICD-0-3 | C67 |
| Methods | qPCR, RNAi, Luciferase reporter assay etc. |
| Sample | cell lines (5637, T24, BLZ-211, BLS-211) |
| Expression Pattern | up-regulated |
| Function Description | In the present study, we showed that lncRNA-UCA1 expression in bladder cancer cells was upregulated by transcription factor CCAAT/enhancer binding protein a (C/EBPa), The transcriptional activation of lncRNA-UCA1 by C/EBPa also contributes to the increased viability and decreased apoptosis of bladder cancer cells. |
| Pubmed ID | 24648007 |
| Year | 2014 |
| Title | Upregulation of long non-coding RNA urothelial carcinoma associated 1 by CCAAT/enhancer binding protein a contributes to bladder cancer cell growth and reduced apoptosis. |
| External Links |
| Links for UCA1 | GenBank HGNC lncrnadb Noncode |
| Links for bladder cancer | Omim Cosmic |
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