Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name UCA1
   Synonyms UCA1, CUDR, LINC00178, NCRNA00178, UCAT1, onco-lncRNA-36
   Region GRCh38_19:15828206-15836326    Sequence
   Ensembl ENSG00000214049
   RefSeq NR_015379
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name bladder cancer
   ICD-0-3 C67  
   Methods qPCR, ISH etc.
   Sample cell lines (BLS-211, BLX-211, BLZ-211 etc.)
   Expression Pattern up-regulated
   Function Description

The expression level of UCA1 was increased in 8 common tumor tissues as compared with that in the corresponding normal tissues. UCA1 mRNA was not detected in normal bladder, normal kidney, renal cancer or hyperplastic prostate tissues, but highly expressed in cancerous bladder tissues. UCA1 gene locates in the cytoplasm, and its mRNA expression level is closely corrrelated to the progression of bladder cancer, indication its potential as a specific molecular marker of bladder cancer.

   Pubmed ID 20117985
   Year 2010
   Title Cellular localization and tissue expression pattern of UCA1, a non-coding RNA.
   External Links
   Links for  UCA1 GenBank       HGNC       lncrnadb       Noncode
   Links for  bladder cancer Omim       Cosmic

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