Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name UCA1
   Synonyms UCA1, CUDR, LINC00178, NCRNA00178, UCAT1, onco-lncRNA-36
   Region GRCh38_19:15828206-15836326    Sequence
   Ensembl ENSG00000214049
   RefSeq NR_015379
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name bladder cancer
   ICD-0-3 C67  
   Methods qPCR, Western blot, RIP
   Sample bladder cancer tissues, cell lines (5637, UMUC2)
   Expression Pattern up-regulated
   Function Description

UCA1 enhances mitochondrial function in bladder cancer cells.These data suggest that UCA1 enhanced mitochondrial function and cell viability through the UCA1/miR-195/ARL2 axis in vitro and in vivo.

   Pubmed ID 29130995
   Year 2017
   Title LncRNA UCA1 Promotes Mitochondrial Function of Bladder Cancer via the MiR-195/ARL2 Signaling Pathway
   External Links
   Links for  UCA1 GenBank       HGNC       lncrnadb       Noncode
   Links for  bladder cancer Omim       Cosmic

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