Detail
LncRNA Name | UCA1 |
Synonyms | UCA1, CUDR, LINC00178, NCRNA00178, UCAT1, onco-lncRNA-36 |
Region | GRCh38_19:15828206-15836326 Sequence |
Ensembl | ENSG00000214049 |
RefSeq | NR_015379 |
Circulating | ✘ |
Drug-resisitant | ✔ |
Prognostic | ✘ |
MiRNA | ✔ |
Variant | ✘ |
TF | ✘ |
Methylation | ✘ |
Cancer Name | ovarian cancer |
ICD-0-3 | C56.9 |
Methods | qPCR, western blot etc. |
Sample | cell lines (SKOV3 and HeyA-8) |
Expression Pattern | up-regulated |
Function Description | Collectively, our study elaborated a novel UCA1/miR-129/ABCB1 regulatory axis underlying PTX resistance of OC cells, providing a potential therapeutic target for OC. |
Pubmed ID | 29777711 |
Year | 2018 |
Title | UCA1 confers paclitaxel resistance to ovarian cancer through miR-129/ABCB1 axis |
External Links |
Links for UCA1 | GenBank HGNC lncrnadb Noncode |
Links for ovarian cancer | Omim Cosmic |
CopyRight © College of Bioinformatics Science and Technology, Harbin Medical University, China.