Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name WT1-AS
   Synonyms WT1-AS, WIT-1, WIT1, WT1-AS1, WT1AS
   Region GRCh38_11:32435518-32458769    Sequence
   Ensembl ENSG00000183242
   RefSeq NR_023920
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name wilms tumor
   ICD-0-3 C64.9  M8960/3
   Methods qPCR etc.
   Sample Bone marrow
   Expression Pattern up-regulated
   Function Description

In most Wilms' tumors, all WT1-AS spliceoforms were overexpressed relative to normal kidney and at comparable levels to fetal kidney.

   Pubmed ID 17940140
   Year 2007
   Title Alternately spliced WT1 antisense transcripts interact with WT1 sense RNA and show epigenetic and splicing defects in cancer.
   External Links
   Links for  WT1-AS GenBank       HGNC       lncrnadb       Noncode
   Links for  wilms tumor Omim       Cosmic

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