Detail
| LncRNA Name | WT1-AS |
| Synonyms | WT1-AS, WIT-1, WIT1, WT1-AS1, WT1AS |
| Region | GRCh38_11:32435518-32458769 Sequence |
| Ensembl | ENSG00000183242 |
| RefSeq | NR_023920 |
| Circulating | ✘ |
| Drug-resisitant | ✔ |
| Prognostic | ✔ |
| MiRNA | ✘ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✔ |
| Cancer Name | colon cancer |
| ICD-0-3 | C18 |
| Methods | microarray, qPCR, RNA pull-down assay etc. |
| Sample | cell line (HCT-117) |
| Expression Pattern | down-regulated |
| Function Description | Quantitative RT-PCR analyses confirmed transcriptional silencing in HCT-116 cells and demethylation-associated reactivation in DKO cells for seven (70%) of the lncRNAs: TP53TG1, NCRNA00028, LOC157627, MIR155HG, WT1AS, C20orf200, and MYCNOS. |
| Pubmed ID | 27821766 |
| Year | 2016 |
| Title | Epigenetic inactivation of the p53-induced long noncoding RNA TP53 target 1 in human cancer. |
| External Links |
| Links for WT1-AS | GenBank HGNC lncrnadb Noncode |
| Links for colon cancer | Omim Cosmic |
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