Detail
| LncRNA Name | WT1-AS |
| Synonyms | WT1-AS, WIT-1, WIT1, WT1-AS1, WT1AS |
| Region | GRCh38_11:32435518-32458769 Sequence |
| Ensembl | ENSG00000183242 |
| RefSeq | NR_023920 |
| Circulating | ✘ |
| Drug-resisitant | ✘ |
| Prognostic | ✘ |
| MiRNA | ✘ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✔ |
| Cancer Name | wilms tumor |
| ICD-0-3 | C64.9 M8960/3 |
| Methods | qPCR, RNAi, Southern blot etc. |
| Sample | Wilms tumor tissues |
| Expression Pattern | differential expression |
| Function Description | Our demonstration of CTCF involvement in AWT1/WT1-AS regulation, allied with the documented genetic lesions of chromosome 16q during Wilms' tumourigenesis, suggested the possibility of epigenetic deregulation at 11p13 arising due to 16q LOH. |
| Pubmed ID | 17210670 |
| Year | 2007 |
| Title | A CTCF-binding silencer regulates the imprinted genes AWT1 and WT1-AS and exhibits sequential epigenetic defects during Wilms' tumourigenesis. |
| External Links |
| Links for WT1-AS | GenBank HGNC lncrnadb Noncode |
| Links for wilms tumor | Omim Cosmic |
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