Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name XIAP-AS1
   Synonyms NA
   Region NA    Sequence
   Ensembl ENSG00000237331
   RefSeq NA
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name gastric cancer
   ICD-0-3 C16  
   Methods qPCR, RIP, Western blot
   Sample gastric cell lines (Bgastric cancer823, Sgastric cancer7901, MKN28, AGS, Mgastric cancer803)
   Expression Pattern up-regulated
   Function Description

In conclusion, our results indicate that XIAP-AS1 is involved in XIAP transcription by interacting with Sp1. Additionally, XIAP-AS1 is a potential target for TRAIL-induced apoptosis in gastric cancer cells.However, there was no significant correlation between the levels of XIAP-AS1 and survival probability (P = 0.07).

   Pubmed ID 28792527
   Year 2017
   Title The long noncoding RNA XIAP-AS1 promotes XIAP transcription by XIAP-AS1 interacting with Sp1 in gastric cancer cells.
   External Links
   Links for  XIAP-AS1 GenBank       HGNC       lncrnadb       Noncode
   Links for  gastric cancer Omim       Cosmic

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