Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name XIST
   Synonyms XIST, DXS1089, DXS399E, LINC00001, NCRNA00001, SXI1, swd66
   Region GRCh38_X:73820651-73852753    Sequence
   Ensembl ENSG00000229807
   RefSeq NR_001564
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name uveal melanoma
   ICD-0-3 C69.9  M8720/3
   Methods qPCR, RNAi, RNA-FISH, Cell migration and invasion assay etc.
   Sample cell lines (HDF, MUM2B, OCM1, OCM1A, OM431, SP6.5, and 293T)
   Expression Pattern down-regulated
   Function Description

To determine the clinical relevance of XIST in UM, we collected human UM tissue samples to examine XIST expression. The expression of XIST was markedly reduced in both female and male UM tissues.

   Pubmed ID 28330694
   Year 2017
   Title CANT1 lncRNA Triggers Efficient Therapeutic Efficacy by Correcting Aberrant lncing Cascade in Malignant Uveal Melanoma.
   External Links
   Links for  XIST GenBank       HGNC       lncrnadb       Noncode
   Links for  uveal melanoma Omim       Cosmic

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