Detail
LncRNA Name | XIST |
Synonyms | XIST, DXS1089, DXS399E, LINC00001, NCRNA00001, SXI1, swd66 |
Region | GRCh38_X:73820651-73852753 Sequence |
Ensembl | ENSG00000229807 |
RefSeq | NR_001564 |
Circulating | ✘ |
Drug-resisitant | ✘ |
Prognostic | ✘ |
MiRNA | ✘ |
Variant | ✘ |
TF | ✘ |
Methylation | ✔ |
Cancer Name | uveal melanoma |
ICD-0-3 | C69.9 M8720/3 |
Methods | qPCR, RNAi, RNA-FISH, Cell migration and invasion assay etc. |
Sample | cell lines (HDF, MUM2B, OCM1, OCM1A, OM431, SP6.5, and 293T) |
Expression Pattern | down-regulated |
Function Description | To determine the clinical relevance of XIST in UM, we collected human UM tissue samples to examine XIST expression. The expression of XIST was markedly reduced in both female and male UM tissues. |
Pubmed ID | 28330694 |
Year | 2017 |
Title | CANT1 lncRNA Triggers Efficient Therapeutic Efficacy by Correcting Aberrant lncing Cascade in Malignant Uveal Melanoma. |
External Links |
Links for XIST | GenBank HGNC lncrnadb Noncode |
Links for uveal melanoma | Omim Cosmic |
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