Detail
LncRNA Name | XIST |
Synonyms | XIST, DXS1089, DXS399E, LINC00001, NCRNA00001, SXI1, swd66 |
Region | GRCh38_X:73820651-73852753 Sequence |
Ensembl | ENSG00000229807 |
RefSeq | NR_001564 |
Circulating | ✘ |
Drug-resisitant | ✘ |
Prognostic | ✘ |
MiRNA | ✘ |
Variant | ✘ |
TF | ✘ |
Methylation | ✘ |
Cancer Name | testicular germ cell tumor |
ICD-0-3 | C62 M9065/3 |
Methods | qPCR etc. |
Sample | testicular germ cell tumor tissues, cell lines (Team-2, JKT-1, ITO-II etc.) |
Expression Pattern | up-regulated |
Function Description | XIST expression was common in seminomatous testicular germ cell tumors (2 of 2 or 100% of seminoma derived cell lines and 10 of 12 or 83% of seminomatous testicular germ cell tumor tissues) but not in nonseminomatous testicular germ cell tumors (0 of 2 or 0% nonseminoma derived cell lines and 2 of 8 or 25% of nonseminomatous testicular germ cell tumor tissues). The current data may suggest the potential oncogenic implications of X chromosomal gain in testicular germ cell tumors. |
Pubmed ID | 12629412 |
Year | 2003 |
Title | The roles of supernumerical X chromosomes and XIST expression in testicular germ cell tumors. |
External Links |
Links for XIST | GenBank HGNC lncrnadb Noncode |
Links for testicular germ cell tumor | Omim Cosmic |
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