Detail
| LncRNA Name | XIST |
| Synonyms | XIST, DXS1089, DXS399E, LINC00001, NCRNA00001, SXI1, swd66 |
| Region | GRCh38_X:73820651-73852753 Sequence |
| Ensembl | ENSG00000229807 |
| RefSeq | NR_001564 |
| Circulating | ✔ |
| Drug-resisitant | ✘ |
| Prognostic | ✘ |
| MiRNA | ✘ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✔ |
| Cancer Name | testicular cancer |
| ICD-0-3 | C62 |
| Methods | qPCR, ISH etc. |
| Sample | peripheral blood, cell lines (NT2/D1, NCCIT, 2102Ep, and S2) |
| Expression Pattern | up-regulated |
| Function Description | XIST was expressed at a higher level in parenchyma with carcinoma in situ, the precursor lesion of seminomas and nonseminomas. Despite the consistent expression of XIST in germ-cell-derived tumors with gain of X chromosomes, methylation of the androgen receptor gene was present in all differentiated but only in a proportion of the undifferentiated nonseminomas. |
| Pubmed ID | 9250171 |
| Year | 1997 |
| Title | X inactivation in human testicular tumors. XIST expression and androgen receptor methylation status. |
| External Links |
| Links for XIST | GenBank HGNC lncrnadb Noncode |
| Links for testicular cancer | Omim Cosmic |
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