Detail
LncRNA Name | XIST |
Synonyms | XIST, DXS1089, DXS399E, LINC00001, NCRNA00001, SXI1, swd66 |
Region | GRCh38_X:73820651-73852753 Sequence |
Ensembl | ENSG00000229807 |
RefSeq | NR_001564 |
Circulating | ✔ |
Drug-resisitant | ✘ |
Prognostic | ✔ |
MiRNA | ✘ |
Variant | ✘ |
TF | ✘ |
Methylation | ✘ |
Cancer Name | hepatocellular carcinoma |
ICD-0-3 | C22.0 M8170/3 |
Methods | qPCR etc. |
Sample | blood, HCC tissues |
Expression Pattern | down-regulated |
Function Description | JPX and XIST levels were significantly decreased in HCC and associated with histological grade and tumor-node-metastasis stage. Low JPX and XIST expression resulted in significantly poor overall survival of HCC. Moreover, plasma JPX levels in patients were lower than that in controls. |
Pubmed ID | 27776968 |
Year | 2017 |
Title | Downregulation of long non-coding RNAs JPX and XIST is associated with the prognosis of hepatocellular carcinoma. |
External Links |
Links for XIST | GenBank HGNC lncrnadb Noncode |
Links for hepatocellular carcinoma | Omim Cosmic |
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