Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name XIST
   Synonyms XIST, DXS1089, DXS399E, LINC00001, NCRNA00001, SXI1, swd66
   Region GRCh38_X:73820651-73852753    Sequence
   Ensembl ENSG00000229807
   RefSeq NR_001564
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name hepatocellular carcinoma
   ICD-0-3 C22.0  M8170/3
   Methods qPCR etc.
   Sample blood, HCC tissues
   Expression Pattern down-regulated
   Function Description

JPX and XIST levels were significantly decreased in HCC and associated with histological grade and tumor-node-metastasis stage. Low JPX and XIST expression resulted in significantly poor overall survival of HCC. Moreover, plasma JPX levels in patients were lower than that in controls.

   Pubmed ID 27776968
   Year 2017
   Title Downregulation of long non-coding RNAs JPX and XIST is associated with the prognosis of hepatocellular carcinoma.
   External Links
   Links for  XIST GenBank       HGNC       lncrnadb       Noncode
   Links for  hepatocellular carcinoma Omim       Cosmic

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