Detail
LncRNA Name | XIST |
Synonyms | XIST, DXS1089, DXS399E, LINC00001, NCRNA00001, SXI1, swd66 |
Region | GRCh38_X:73820651-73852753 Sequence |
Ensembl | ENSG00000229807 |
RefSeq | NR_001564 |
Circulating | ✘ |
Drug-resisitant | ✘ |
Prognostic | ✘ |
MiRNA | ✘ |
Variant | ✘ |
TF | ✘ |
Methylation | ✘ |
Cancer Name | breast cancer |
ICD-0-3 | C50 |
Methods | microarray, FISH etc. |
Sample | breast cancer tissues |
Expression Pattern | differential expression |
Function Description | The intratumoral and intertumoral variability in XIST RNA domain number in BRCA1 tumors correlates with chromosomal genetic abnormalities, including gains, losses, reduplications, and rearrangements of the X-chromosome. Finally, we also show the necessity for combined global and single-cell approaches in the assessment of tumors with such a high degree of heterogeneity. |
Pubmed ID | 17545591 |
Year | 2007 |
Title | X inactive-specific transcript RNA coating and genetic instability of the X chromosome in BRCA1 breast tumors. |
External Links |
Links for XIST | GenBank HGNC lncrnadb Noncode |
Links for breast cancer | Omim Cosmic |
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