Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

LncRNA centric

Cancer centric

Advanced search

Drug resistant

Circulating

Prognosis

Detail


   LncRNA Name XIST
   Synonyms XIST, DXS1089, DXS399E, LINC00001, NCRNA00001, SXI1, swd66
   Region GRCh38_X:73820651-73852753    Sequence
   Ensembl ENSG00000229807
   RefSeq NR_001564
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name breast cancer
   ICD-0-3 C50  
   Methods microarray, FISH etc.
   Sample breast cancer tissues
   Expression Pattern differential expression
   Function Description

The intratumoral and intertumoral variability in XIST RNA domain number in BRCA1 tumors correlates with chromosomal genetic abnormalities, including gains, losses, reduplications, and rearrangements of the X-chromosome. Finally, we also show the necessity for combined global and single-cell approaches in the assessment of tumors with such a high degree of heterogeneity.

   Pubmed ID 17545591
   Year 2007
   Title X inactive-specific transcript RNA coating and genetic instability of the X chromosome in BRCA1 breast tumors.
   External Links
   Links for  XIST GenBank       HGNC       lncrnadb       Noncode
   Links for  breast cancer Omim       Cosmic

CopyRight © College of Bioinformatics Science and Technology, Harbin Medical University, China.