Detail
| LncRNA Name | XIST |
| Synonyms | XIST, DXS1089, DXS399E, LINC00001, NCRNA00001, SXI1, swd66 |
| Region | GRCh38_X:73820651-73852753 Sequence |
| Ensembl | ENSG00000229807 |
| RefSeq | NR_001564 |
| Circulating | ✘ |
| Drug-resisitant | ✘ |
| Prognostic | ✘ |
| MiRNA | ✔ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✘ |
| Cancer Name | osteosarcoma |
| ICD-0-3 | M9180/3 |
| Methods | qPCR, Western blot, Luciferase Reporter Assays |
| Sample | osteosarcoma tissues, cell lines (U2OS, Saos-2, MG63, and MNNG/HOS) |
| Expression Pattern | up-regulated |
| Function Description | XIST expression was significantly increased in osteosarcoma tissues and cell lines by LncRNA Profiler and qRT-PCR. The competing relationship between XIST and miR-320b was confirmed by Luciferase report assay. |
| Pubmed ID | 28409547 |
| Year | 2017 |
| Title | Long Non-Coding RNA XIST Promotes Osteosarcoma Progression by Targeting Ras-Related Protein RAP2B via miR-320b |
| External Links |
| Links for XIST | GenBank HGNC lncrnadb Noncode |
| Links for osteosarcoma | Omim Cosmic |
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