Detail
LncRNA Name | XIST |
Synonyms | XIST, DXS1089, DXS399E, LINC00001, NCRNA00001, SXI1, swd66 |
Region | GRCh38_X:73820651-73852753 Sequence |
Ensembl | ENSG00000229807 |
RefSeq | NR_001564 |
Circulating | ✘ |
Drug-resisitant | ✘ |
Prognostic | ✘ |
MiRNA | ✘ |
Variant | ✘ |
TF | ✘ |
Methylation | ✘ |
Cancer Name | breast cancer |
ICD-0-3 | C50 |
Methods | qPCR, RNAi, RNA-FISH, DNA-FISH, Methylation assay etc. |
Sample | breast cancer tissues, cell lines (MCF7, MDA MB 231, T47D and HCC1937) |
Expression Pattern | up-regulated |
Function Description | XIST RNA levels comparable to those of non-BLC and significantly higher than those detected in sporadic BLC. In this tumor cell line XIST shows a misbehaviour, because it is expressed by an active X chromosome and does not stably coat the XIST expressing X chromosome. |
Pubmed ID | 19440381 |
Year | 2009 |
Title | Misbehaviour of XIST RNA in breast cancer cells. |
External Links |
Links for XIST | GenBank HGNC lncrnadb Noncode |
Links for breast cancer | Omim Cosmic |
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