Detail
| LncRNA Name | XIST |
| Synonyms | XIST, DXS1089, DXS399E, LINC00001, NCRNA00001, SXI1, swd66 |
| Region | GRCh38_X:73820651-73852753 Sequence |
| Ensembl | ENSG00000229807 |
| RefSeq | NR_001564 |
| Circulating | ✘ |
| Drug-resisitant | ✘ |
| Prognostic | ✔ |
| MiRNA | ✘ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✘ |
| Cancer Name | osteosarcoma |
| ICD-0-3 | M9180/3 |
| Methods | qPCR, RIP, Western Blot etc. |
| Sample | Human osteosarcoma cell lines (U2OS, Saos-2, 143B, MG-63, HOS), OS tissues |
| Expression Pattern | up-regulated |
| Function Description | Taking all into account, Xist may function in promoting OS cell proliferation and may potentially serve as a novel biomarker and therapeutic target for OS.Due to recent advancements in multimodal treatments, the 5-year survival rate of OS patients has significantly improved over the past decades. |
| Pubmed ID | 29254174 |
| Year | 2017 |
| Title | Upregulation of long noncoding RNA Xist promotes proliferation of osteosarcoma by epigenetic silencing of P21. |
| External Links |
| Links for XIST | GenBank HGNC lncrnadb Noncode |
| Links for osteosarcoma | Omim Cosmic |
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