Detail
LncRNA Name | XIST |
Synonyms | XIST, DXS1089, DXS399E, LINC00001, NCRNA00001, SXI1, swd66 |
Region | GRCh38_X:73820651-73852753 Sequence |
Ensembl | ENSG00000229807 |
RefSeq | NR_001564 |
Circulating | ✘ |
Drug-resisitant | ✘ |
Prognostic | ✘ |
MiRNA | ✔ |
Variant | ✘ |
TF | ✘ |
Methylation | ✘ |
Cancer Name | colorectal cancer |
ICD-0-3 | C19.9 |
Methods | qPCR, Western blot etc. |
Sample | colorectal cancer tissues, cell lines (LOVO, HCT116, SW620, SW480 and HT29) |
Expression Pattern | up-regulated |
Function Description | The expression level of XIST was significantly increased in both CRC tissues sample and CRC cells.XIST promoted CRC cell proliferation by affecting the cell cycle. In addition, XIST and miR-132-3p were inhibited by each other reciprocally. |
Pubmed ID | 28730777 |
Year | 2017 |
Title | Long non-coding RNA XIST functions as an oncogene in human colorectal cancer by targeting miR-132-3p |
External Links |
Links for XIST | GenBank HGNC lncrnadb Noncode |
Links for colorectal cancer | Omim Cosmic |
CopyRight © College of Bioinformatics Science and Technology, Harbin Medical University, China.