Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name XIST
   Synonyms XIST, DXS1089, DXS399E, LINC00001, NCRNA00001, SXI1, swd66
   Region GRCh38_X:73820651-73852753    Sequence
   Ensembl ENSG00000229807
   RefSeq NR_001564
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name colorectal cancer
   ICD-0-3 C19.9  
   Methods qPCR, Western blot etc.
   Sample colorectal cancer tissues, cell lines (LOVO, HCT116, SW620, SW480 and HT29)
   Expression Pattern up-regulated
   Function Description

The expression level of XIST was significantly increased in both CRC tissues sample and CRC cells.XIST promoted CRC cell proliferation by affecting the cell cycle. In addition, XIST and miR-132-3p were inhibited by each other reciprocally.

   Pubmed ID 28730777
   Year 2017
   Title Long non-coding RNA XIST functions as an oncogene in human colorectal cancer by targeting miR-132-3p
   External Links
   Links for  XIST GenBank       HGNC       lncrnadb       Noncode
   Links for  colorectal cancer Omim       Cosmic

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