Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name XIST
   Synonyms XIST, DXS1089, DXS399E, LINC00001, NCRNA00001, SXI1, swd66
   Region GRCh38_X:73820651-73852753    Sequence
   Ensembl ENSG00000229807
   RefSeq NR_001564
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name cervical cancer
   ICD-0-3 C53  
   Methods qPCR, Western blot, Luciferase reporter assay, etc.
   Sample cervical cancer tissues, cell lines (Hela, Caski, C4-1, Siha, GH329)
   Expression Pattern up-regulated
   Function Description

XIST upregulated Fus through competitively binding with miR-200a. patients with high expression of XIST had a lower survival rate than those with low expression of XIST

   Pubmed ID 29909347
   Year 2018
   Title LncRNA XIST accelerates cervical cancer progression via upregulating Fus through competitively binding with miR-200a.
   External Links
   Links for  XIST GenBank       HGNC       lncrnadb       Noncode
   Links for  cervical cancer Omim       Cosmic

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