Detail
| LncRNA Name | C5orf66-AS1 |
| Synonyms | C5orf66-AS1, CTC-276P9.1, Epist |
| Region | GRCh38_5:135038831-135040047 Sequence |
| Ensembl | ENSG00000249082 |
| RefSeq | NR_105049 |
| Circulating | ✘ |
| Drug-resisitant | ✘ |
| Prognostic | ✔ |
| MiRNA | ✘ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✘ |
| Cancer Name | esophageal squamous cell cancer |
| ICD-0-3 | |
| Methods | microarray, qPCR etc. |
| Sample | cell lines (KYSE510, KYSE450, KYSE150, KYSE30, EC109, TE-1) |
| Expression Pattern | down-regulated |
| Function Description | We identified a novel nuclear-retained lncRNA, named Epist, which is generally highly expressed in esophagus, and which is down-regulated during ESCC progression. Epist over-expression and knockdown studies further suggest that Epist inhibits the metastasis, acting as a tumor suppressor in ESCC. Collectively |
| Pubmed ID | 26158411 |
| Year | 2015 |
| Title | Transcriptome profiling of esophageal squamous cell carcinoma reveals a long noncoding RNA acting as a tumor suppressor |
| External Links |
| Links for C5orf66-AS1 | GenBank HGNC lncrnadb Noncode |
| Links for esophageal squamous cell cancer | Omim Cosmic |
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