Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name ZEB1-AS1
   Synonyms NR_024284
   Region GRCh38_10:31206278-31320447    Sequence
   Ensembl ENSG00000237036
   RefSeq NR_024284
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name gastric cancer
   ICD-0-3 C16  
   Methods qPCR, Western blot etc.
   Sample cell lines (NCI-N87, SNU-1, AGS, MKN-45)
   Expression Pattern up-regulated
   Function Description

ZEB1-AS1 regulated gastric cancer cells migration, invasion and EMT process.ZEB1-AS1 positively regulated ZEB1 expression in gastric cancer cells, and had a strongly positive correlation with ZEB1 expression in gastric cancer tissues.Rescued-function studies showed ZEB1 was critical for ZEB1-AS1 induced gastric cancer cells migration, invasion and EMT process.

   Pubmed ID 29113674
   Year 2017
   Title LncRNA ZEB1-AS1 predicts unfavorable prognosis in gastric cancer
   External Links
   Links for  ZEB1-AS1 GenBank       HGNC       lncrnadb       Noncode
   Links for  gastric cancer Omim       Cosmic

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