Detail
LncRNA Name | ZEB1-AS1 |
Synonyms | NR_024284 |
Region | GRCh38_10:31206278-31320447 Sequence |
Ensembl | ENSG00000237036 |
RefSeq | NR_024284 |
Circulating | ✘ |
Drug-resisitant | ✘ |
Prognostic | ✔ |
MiRNA | ✘ |
Variant | ✘ |
TF | ✘ |
Methylation | ✘ |
Cancer Name | gastric cancer |
ICD-0-3 | C16 |
Methods | qPCR, Western blot etc. |
Sample | cell lines (NCI-N87, SNU-1, AGS, MKN-45) |
Expression Pattern | up-regulated |
Function Description | ZEB1-AS1 regulated gastric cancer cells migration, invasion and EMT process.ZEB1-AS1 positively regulated ZEB1 expression in gastric cancer cells, and had a strongly positive correlation with ZEB1 expression in gastric cancer tissues.Rescued-function studies showed ZEB1 was critical for ZEB1-AS1 induced gastric cancer cells migration, invasion and EMT process. |
Pubmed ID | 29113674 |
Year | 2017 |
Title | LncRNA ZEB1-AS1 predicts unfavorable prognosis in gastric cancer |
External Links |
Links for ZEB1-AS1 | GenBank HGNC lncrnadb Noncode |
Links for gastric cancer | Omim Cosmic |
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