Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name CAHM
   Synonyms CAHM, LINC00468
   Region GRCh38_6:163413065-163413960    Sequence
   Ensembl ENSG00000270419
   RefSeq NR_037593
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name colorectal cancer
   ICD-0-3 C19.9  
   Methods qPCR, MSP-PCR etc.
   Sample blood, CRC tissues
   Expression Pattern down-regulated
   Function Description

A reverse transcriptase-qPCR assay showed that CAHM RNA levels correlated negatively with CAHM % methylation, and therefore CAHM gene expression is typically decreased in CRC. Both the frequency of detection and the amount of methylated CAHM DNA released into plasma increased with increasing cancer stage.

   Pubmed ID 24799664
   Year 2014
   Title CAHM, a long non-coding RNA gene hypermethylated in colorectal neoplasia.
   External Links
   Links for  CAHM GenBank       HGNC       lncrnadb       Noncode
   Links for  colorectal cancer Omim       Cosmic

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