Detail
| LncRNA Name | ZEB1-AS1 |
| Synonyms | NR_024284 |
| Region | GRCh38_10:31206278-31320447 Sequence |
| Ensembl | ENSG00000237036 |
| RefSeq | NR_024284 |
| Circulating | ✘ |
| Drug-resisitant | ✘ |
| Prognostic | ✘ |
| MiRNA | ✔ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✘ |
| Cancer Name | colorectal cancer |
| ICD-0-3 | C19.9 |
| Methods | Flow cytometry assay, qPCR, Western blot, etc. |
| Sample | Six CRC cell lines (RKO, Caco2, DLD1, HCT116, LOVO, SW480), HEK293T cells (a human non-CRC cell line) |
| Expression Pattern | up-regulated |
| Function Description | In summary, our findings provide the evidence supporting the role of ZEB1-AS1 as an oncogene in CRC. Our study also demonstrates that miR-181a-5p targets not only protein-coding genes but also the lncRNA ZEB1-AS1. |
| Pubmed ID | 29886791 |
| Year | 2018 |
| Title | The lncRNA ZEB1-AS1 sponges miR-181a-5p to promote colorectal cancer cell proliferation by regulating Wnt/β-catenin signaling. |
| External Links |
| Links for ZEB1-AS1 | GenBank HGNC lncrnadb Noncode |
| Links for colorectal cancer | Omim Cosmic |
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