Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name ZFAS1
   Synonyms ZFAS1, C20orf199, HSUP1, HSUP2, NCRNA00275, ZNFX1-AS1
   Region GRCh38_20:49278178-49295738    Sequence
   Ensembl ENSG00000177410
   RefSeq NR_003604
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name ovarian cancer
   ICD-0-3 C56.9  
   Methods qPCR etc.
   Sample cell lines (A2008, HeyA8, and HeyC2)
   Expression Pattern up-regulated
   Function Description

In vitro experiment results showed that the ZFAS1 expression level was upregulated in A2008, HeyA8, and HeyC2 cell lines treated with cisplatin compared with the control group, which indicates that cisplatin could increase the ZFAS1 expression level in ovarian cancer cells.

   Pubmed ID 28154416
   Year 2017
   Title Long noncoding RNA expression signature to predict platinum-based chemotherapeutic sensitivity of ovarian cancer patients.
   External Links
   Links for  ZFAS1 GenBank       HGNC       lncrnadb       Noncode
   Links for  ovarian cancer Omim       Cosmic

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