Detail
| LncRNA Name | ZFAS1 |
| Synonyms | ZFAS1, C20orf199, HSUP1, HSUP2, NCRNA00275, ZNFX1-AS1 |
| Region | GRCh38_20:49278178-49295738 Sequence |
| Ensembl | ENSG00000177410 |
| RefSeq | NR_003604 |
| Circulating | ✘ |
| Drug-resisitant | ✘ |
| Prognostic | ✘ |
| MiRNA | ✘ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✘ |
| Cancer Name | breast cancer |
| ICD-0-3 | C50 |
| Methods | microarray, Northern blot, ISH etc. |
| Sample | breast cancer tissues |
| Expression Pattern | down-regulated |
| Function Description | The result shows ZFAS1 expression is decreased in ductal carcinoma relative to normal epithelial cells. We propose a functional role for Zfas1/ ZFAS1 in the regulation of alveolar development and epithelial cell differentiation in the mammary gland, which, together with its dysregulation in human breast cancer, suggests ZFAS1 as a putative tumor suppressor gene. |
| Pubmed ID | 21460236 |
| Year | 2011 |
| Title | SNORD-host RNA Zfas1 is a regulator of mammary development and a potential marker for breast cancer. |
| External Links |
| Links for ZFAS1 | GenBank HGNC lncrnadb Noncode |
| Links for breast cancer | Omim Cosmic |
CopyRight © College of Bioinformatics Science and Technology, Harbin Medical University, China.