Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name ZFAS1
   Synonyms ZFAS1, C20orf199, HSUP1, HSUP2, NCRNA00275, ZNFX1-AS1
   Region GRCh38_20:49278178-49295738    Sequence
   Ensembl ENSG00000177410
   RefSeq NR_003604
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name nasopharyngeal cancer
   ICD-0-3 C11  
   Methods qPCR, Western blot, etc.
   Sample nasopharyngeal cancer tissues, cell lines (CNE-1, CNE-2, HNE-1, NP-69, HONE-1, SUNE-1)
   Expression Pattern up-regulated
   Function Description

ZFAS1 was overexpressed in NPC and was significantly related to tumor size, lymph node metastasis and poor prognosis of NPC. ZFAS1 could promote NPC by activating Wnt/B-catenin pathway.

   Pubmed ID 29917194
   Year 2018
   Title Long non-coding RAN ZFAS1 promotes nasopharyngeal carcinoma through activation of Wnt/β-catenin pathway.
   External Links
   Links for  ZFAS1 GenBank       HGNC       lncrnadb       Noncode
   Links for  nasopharyngeal cancer Omim       Cosmic

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