Detail
| LncRNA Name | ZNF667-AS1 |
| Synonyms | NA |
| Region | GRCh38_19:56477250-56500666 Sequence |
| Ensembl | ENSG00000166770 |
| RefSeq | NR_036522 |
| Circulating | ✘ |
| Drug-resisitant | ✘ |
| Prognostic | ✔ |
| MiRNA | ✘ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✘ |
| Cancer Name | cervical cancer |
| ICD-0-3 | C53 M8070/3 |
| Methods | qPCR, microarray, western blot |
| Sample | cell lines(SiHa) |
| Expression Pattern | down-regulated |
| Function Description | the expression of LncRNA ZNF667-AS1 in cervical cancer was significantly lower than that in normal cervical tissues.the expression of LncRNA ZNF667-AS1 in cervical cancer tissues was lower than that in normal cervical tissues, which was consistent with that of TCGA.the expression of LncRNA ZNF667-AS1 was correlated with the total survival, tumor size and FIGO stage.Compared with the negative control group, the proliferation ability and cell cloning ability of cells with over-expressed LncRNA ZNF667-AS1 were significantly decreased, indicating that overexpression of ZNF667-AS1 inhibited the proliferation of SiHa cells. |
| Pubmed ID | 29243775 |
| Year | 2017 |
| Title | Independent prognostic Factor of low-expressed LncRNA ZNF667-AS1 for cervical cancer and inhibitory function on the proliferation of cervical canc |
| External Links |
| Links for ZNF667-AS1 | GenBank HGNC lncrnadb Noncode |
| Links for cervical cancer | Omim Cosmic |
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