Detail
| LncRNA Name | ZNRD1-AS1 |
| Synonyms | ZNRD1ASP, C6orf12, HCG8, HCGVIII, HCGVIII-1, HTEX4, NCRNA00171, TCTEX4, ZNRD1-AS, ZNRD1-AS1, ZNRD1AS, ZNRD1AS1 |
| Region | NA Sequence |
| Ensembl | NA |
| RefSeq | NA |
| Circulating | ✔ |
| Drug-resisitant | ✘ |
| Prognostic | ✘ |
| MiRNA | ✘ |
| Variant | ✔ |
| TF | ✘ |
| Methylation | ✘ |
| Cancer Name | lung cancer |
| ICD-0-3 | C34 |
| Methods | qPCR, Genotyping etc. |
| Sample | blood |
| Expression Pattern | down-regulated |
| Function Description | we first evaluated the expression ZNRD1-AS1 and ZNRD1 among lung cancer tissues and corresponding normal tissues, which showed higher expression of ZNRD1-AS1 and lower expression of ZNRD1. To reveal the underlying mechanisms, we then investigated the associations between ZNRD1 eQTLs SNPs in ZNRD1-AS1 and risk of lung cancer in Han Chinese populations. G allele of SNP rs9261204 was significantly associated with an increased risk of lung cancer when compared with A allele. A weaker, but similar effect was also observed in bladder cancer. SNP rs3757328 was also associated with increased risk of lung cancer. |
| Pubmed ID | 27166266 |
| Year | 2016 |
| Title | Strong evidence for LncRNA ZNRD1-AS1, and its functional Cis-eQTL locus contributing more to the susceptibility of lung cancer |
| External Links |
| Links for ZNRD1-AS1 | GenBank HGNC lncrnadb Noncode |
| Links for lung cancer | Omim Cosmic |
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