Detail
| LncRNA Name | CASC15 |
| Synonyms | CASC15, LINC00340, lnc-SOX4-1 |
| Region | GRCh38_6:21664772-22368328 Sequence |
| Ensembl | ENSG00000272168 |
| RefSeq | NR_015410 |
| Circulating | ✘ |
| Drug-resisitant | ✘ |
| Prognostic | ✔ |
| MiRNA | ✘ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✘ |
| Cancer Name | neuroblastoma |
| ICD-0-3 | M9500/3 |
| Methods | RNA-seq, qPCR, RNAi, Luciferase reporter assay, RNA-FISH etc. |
| Sample | neuroblastoma cell lines |
| Expression Pattern | down-regulated |
| Function Description | Here we report that the most highly significant single-nucleotide polymorphism (SNP) associations reside within CASC15, a long noncoding RNA that we define as a tumor suppressor at 6p22. Low-level expression of a short CASC15 isoform (CASC15-S) associated highly with advanced neuroblastoma and poor patient survival. |
| Pubmed ID | 26100672 |
| Year | 2015 |
| Title | CASC15-S Is a Tumor Suppressor lncRNA at the 6p22 Neuroblastoma Susceptibility Locus. |
| External Links |
| Links for CASC15 | GenBank HGNC lncrnadb Noncode |
| Links for neuroblastoma | Omim Cosmic |
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