Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name CASC2
   Synonyms CASC2, C10orf5
   Region GRCh38_10:118046279-118210153    Sequence
   Ensembl ENSG00000177640
   RefSeq NR_026939
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name colorectal cancer
   ICD-0-3 C19.9  
   Methods qPCR, Luciferase reporter assay
   Sample colorectal adenocarcinoma cell line LS174T
   Expression Pattern down-regulated
   Function Description

However, contrary to what we expected and reported by others, lncCASC2 quantity was significantly reduced in LNA treated LS174T cells compared to the scrambled treated and normal untreated cells (P < 0.05).

   Pubmed ID 29456985
   Year 2018
   Title Evaluation of miR-21 Inhibition and its Impact on Cancer Susceptibility Candidate 2 Long Noncoding RNA in Colorectal Cancer Cell Line.
   External Links
   Links for  CASC2 GenBank       HGNC       lncrnadb       Noncode
   Links for  colorectal cancer Omim       Cosmic

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