Detail
| LncRNA Name | CASC2 |
| Synonyms | CASC2, C10orf5 |
| Region | GRCh38_10:118046279-118210153 Sequence |
| Ensembl | ENSG00000177640 |
| RefSeq | NR_026939 |
| Circulating | ✘ |
| Drug-resisitant | ✘ |
| Prognostic | ✔ |
| MiRNA | ✘ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✘ |
| Cancer Name | pancreatic cancer |
| ICD-0-3 | C25 |
| Methods | qPCR, Western blot,Luciferase reporter assay ,ChIP etc. |
| Sample | pancreatic cancer tissues,cell line (HPDE,SW1990,BxPC-3, AsPC-1, CFPAC-1 and PANC-1) |
| Expression Pattern | down-regulated |
| Function Description | a lower CASC2 expression in PC was related with a poorer prognosis. CASC2 gene possessed a HNF1A-responsive element (CASC2-HNF1A RE); HNF1A could promote CASC2 expression through direct binding to CASC2-HNF1A RE. |
| Pubmed ID | 28865121 |
| Year | 2017 |
| Title | HNF1A/CASC2 regulates pancreatic cancer cell proliferation through PTEN/Akt signaling. |
| External Links |
| Links for CASC2 | GenBank HGNC lncrnadb Noncode |
| Links for pancreatic cancer | Omim Cosmic |
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