Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name CASC9
   Synonyms CASC9, ESCCAL-1, ESSCAL1, LINC00981, ESCCAL-1
   Region GRCh38_8:75223404-75324741    Sequence
   Ensembl ENSG00000249395
   RefSeq NR_103848
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name non small cell lung cancer
   ICD-0-3 C34  M8046/3
   Methods microarray, qPCR, RNAi, Cell proliferation assay etc.
   Sample cell lines (PC9, PC9G)
   Expression Pattern up-regulated
   Function Description

CASC9 expression was upregulated in PC9G and knockdown of its expression could increase the sensitivity of PC9G cells to gefitinib.

   Pubmed ID 28040594
   Year 2017
   Title Transcriptome analysis of EGFR tyrosine kinase inhibitors resistance associated long noncoding RNA in non-small cell lung cancer.
   External Links
   Links for  CASC9 GenBank       HGNC       lncrnadb       Noncode
   Links for  non small cell lung cancer Omim       Cosmic

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