Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name CASC9
   Synonyms CASC9, ESCCAL-1, ESSCAL1, LINC00981, ESCCAL-1
   Region GRCh38_8:75223404-75324741    Sequence
   Ensembl ENSG00000249395
   RefSeq NR_103848
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name esophageal squamous cell cancer
   ICD-0-3  
   Methods qPCR, Western blot
   Sample esophageal squamous cell carcinoma tissues, cell lines (KYSE30,KYSE150, TE-1, Eca-109,HEEpiC)
   Expression Pattern up-regulated
   Function Description

CASC9 expression is independent Multivariate analysis showed prognostic indicators of overall survival and disease-free survival.inhibition of CASC9 can inhibit the proliferation, migration and invasion of ESCC. Abnormal CASC9 expression can regulate the expression level of markers EMT.

   Pubmed ID 29424900
   Year 2018
   Title LncRNA CASC9 promotes tumorigenesis by affecting EMT and predicts poor prognosis in esophageal squamous cell cancer.
   External Links
   Links for  CASC9 GenBank       HGNC       lncrnadb       Noncode
   Links for  esophageal squamous cell cancer Omim       Cosmic

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