Detail
| LncRNA Name | CCAL |
| Synonyms | NA |
| Region | NA Sequence |
| Ensembl | NA |
| RefSeq | NA |
| Circulating | ✘ |
| Drug-resisitant | ✔ |
| Prognostic | ✔ |
| MiRNA | ✘ |
| Variant | ✘ |
| TF | ✘ |
| Methylation | ✘ |
| Cancer Name | colorectal cancer |
| ICD-0-3 | C19.9 |
| Methods | microarray, qPCR etc. |
| Sample | CRC tissues |
| Expression Pattern | up-regulated |
| Function Description | We identified colorectal cancer-associated lncRNA (CCAL) as a key regulator of CRC progression. Patients whose tumours had high CCAL expression had a shorter overall survival and a worse response to adjuvant chemotherapy than patients whose tumours had low CCAL expression.Our results suggest that CCAL is a crucial oncogenic regulator involved in CRC tumorigenesis and progression. |
| Pubmed ID | 25994219 |
| Year | 2015 |
| Title | Long non-coding RNA CCAL regulates colorectal cancer progression by activating Wnt/B-Catenin signalling pathway via suppression of activator protein 2a. |
| External Links |
| Links for CCAL | GenBank HGNC lncrnadb Noncode |
| Links for colorectal cancer | Omim Cosmic |
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