Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

LncRNA centric

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   LncRNA Name CCAL
   Synonyms NA
   Region NA    Sequence
   Ensembl NA
   RefSeq NA
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name gastric cancer
   ICD-0-3 C16  
   Methods RT-PCR, Western blot
   Sample GC tumor tissue, GC cell lines (BGC-823, MKN-45, AGS, SGC-7901, MGC-803)
   Expression Pattern up-regulated
   Function Description

CCAL was upregulated in gastric cancer cell lines. Patients whose tumors had high CCAL expression had a shorter overall survival than patients whose tumors had low CCAL expression Overexpression CCAL promoted the proliferation, migration and invasion of GC by regulating the expression of myc.

   Pubmed ID 29441950
   Year 2018
   Title Long noncoding RNA CCAL promotes gastric cancer cell proliferation and migration in a Myc dependent way.
   External Links
   Links for  CCAL GenBank       HGNC       lncrnadb       Noncode
   Links for  gastric cancer Omim       Cosmic

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