Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name CCAT1
   Synonyms CCAT1, CARLo-5, onco-lncRNA-40
   Region GRCh38_8:127207382-127219268    Sequence
   Ensembl ENSG00000247844
   RefSeq NR_108049
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name osteosarcoma
   ICD-0-3  M9180/3
   Methods qPCR, RNAi etc.
   Sample osteosarcoma tissues, cell lines (143b, KHOS, MG-63, and U2OS)
   Expression Pattern up-regulated
   Function Description

Our findings revealed that CCAT1 was upregulated in osteosarcoma tissues and cells, and was involved in the proliferation and migration of osteosarcoma via regulating miR-148a/phosphatidyl inositol 3-kinase interacting protein 1 (PIK3IP1) signal pathway.

   Pubmed ID 28549102
   Year 2017
   Title Long non-coding RNA CCAT1/miR-148a axis promotes osteosarcoma proliferation and migration through regulating PIK3IP1
   External Links
   Links for  CCAT1 GenBank       HGNC       lncrnadb       Noncode
   Links for  osteosarcoma Omim       Cosmic

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