Detail
LncRNA Name | CCAT1 |
Synonyms | CCAT1, CARLo-5, onco-lncRNA-40 |
Region | GRCh38_8:127207382-127219268 Sequence |
Ensembl | ENSG00000247844 |
RefSeq | NR_108049 |
Circulating | ✘ |
Drug-resisitant | ✘ |
Prognostic | ✘ |
MiRNA | ✔ |
Variant | ✘ |
TF | ✘ |
Methylation | ✘ |
Cancer Name | laryngeal squamous cell cancer |
ICD-0-3 | C32.3 |
Methods | qPCR, Western blot |
Sample | laryngeal squamous cell carcinoma tissues |
Expression Pattern | up-regulated |
Function Description | CCAT1 expression was upregulated in LSCC tissues compared with the normal adjacent tissues. We also demonstrated that CCAT1 overexpression suppressed the expression of let-7 and enhanced the expression of HMGA2 and Myc, the direct target genes of let-7. |
Pubmed ID | 27830017 |
Year | 2016 |
Title | CCAT1 promotes laryngeal squamous cell carcinoma cell proliferation and invasion |
External Links |
Links for CCAT1 | GenBank HGNC lncrnadb Noncode |
Links for laryngeal squamous cell cancer | Omim Cosmic |
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