Lnc2Cancer

Experimentally Supported Human LncRNA and Cancer Associations Database

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   LncRNA Name AC105461.1
   Synonyms NA
   Region GRCh38_2:231978488-232015720    Sequence
   Ensembl NA
   RefSeq NA
   Circulating
   Drug-resisitant
   Prognostic
   MiRNA
   Variant
   TF
   Methylation
   Cancer Name colorectal cancer
   ICD-0-3 C19.9  
   Methods qPCR
   Sample colorectal cancer tissues, cell lines (SW620, SW480, HT29, HCT116, and Caco-2)
   Expression Pattern up-regulated
   Function Description

As a result, we found that AC105461.1 overexpression reduced the percentage of CD133+ CD44+, whereas its knockdown increased the percentage of CD133+CD44+.

   Pubmed ID 28496335
   Year 2017
   Title Knockdown of a DIS3L2 promoter upstream long noncoding RNA (AC105461.1) enhances colorectal cancer stem cell properties in vitro by down-regulating DIS3L2
   External Links
   Links for  AC105461.1 GenBank       HGNC       lncrnadb       Noncode
   Links for  colorectal cancer Omim       Cosmic

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